BDBM136861 US10231967, Example 98::US8865911, 98::US9918985, Example 98

SMILES CO[C@H]1CC[C@@]2(Cc3ccc(cc3[C@@]22N=C(C)C(N)=N2)-c2cc(OC)ccc2F)CC1

InChI Key InChIKey=JJDMMVKGGCIWNE-WDNCENIBSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136861   

TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM136861(US10231967, Example 98 | US8865911, 98 | US9918985...)
Affinity DataIC50:  1.5nMpH: 9.2Assay Description:TR-FRET AssayThe beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA...More data for this Ligand-Target Pair
In DepthDetails US Patent